Dovenex ointment also knows as calcipotriene ointment, is a topical ointment used for the treatment of plauque psoriasis. Dovonex ointment contains calcipotriene 50 µg/g in an ointment base of dibasic sodium phosphate, edetate disodium, mineral oil, petrolatum, propylene glycol, tocopherol, steareth-2 and water.
Psoriasis is a chronic, autoimmune disease that appears on the skin. It occurs when the immune system sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is not contagious. There are five types of psoriasis: plaque, guttate, inverse, pustular and erythrodermic.
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The most common form, plaque psoriasis, appears as raised, red patches or lesions covered with a silvery white buildup of dead skin cells, called scale. Psoriasis can occur on any part of the body and is associated with other serious health conditions, such as diabetes, heart disease and depression. According to the National Institutes of Health, as many as 7.5 million Americans have psoriasis.
No one knows exactly what causes psoriasis. However, it is understood that the immune system and genetics play major roles in its development. Most researchers agree that the immune system is somehow mistakenly triggered, which causes a series of events, including acceleration of skin cell growth. A normal skin cell matures and falls off the body in 28 to 30 days. A skin cell in a patient with psoriasis takes only 3 to 4 days to mature and instead of falling off (shedding), the cells pile up on the surface of the skin, forming psoriasis lesions.
Scientists believe that at least 10 percent of the general population inherits one or more of the genes that create a predisposition to psoriasis. However, only 2 percent to 3 percent of the population develops the disease. Researchers believe that for a person to develop psoriasis, the individual must have a combination of the genes that cause psoriasis and be exposed to specific external factors known as "triggers."
The normal dosage for dovenex ointment for adults is to apply to skin at least once or twice a day, or as prescribed by your doctor. Your doctor will tell you if he or she wants you to cover but normally it is left uncovered and rubbed into the skin until no more of the ointment can be seen. It is important to only apply to affected areas and to keep away from water and clothing until the skin has absorbed it completely.
Side effects include: itching, burning of the skin, redness of the skin, sensitivity to light, flushing of the skin, inflammation of the skin, worsening conditions of the skin and irritation of the area in use. Not all people will feel or notice the above mentioned side effects but if you should have any questions or concerns you should contact your doctor immediately.
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